Regenerative Disc Therapy
Chronic low back pain can begin deep inside a spinal disc, where small tears, inflammation, and irritated nerve fibers build over time. Our COOLIEF® TransDiscal® Disc Biacuplasty combines cooled radiofrequency technology to calm disc-related pain signals with regenerative biologics, including stem cells, exosomes, and PRP, to support natural healing. When symptoms arise from other sources, such as irritated facet joints or compression of nearby nerves, our physicians may consider other targeted options, including image-guided injections of stem cells and exosomes into or around the affected structures. Treatment is tailored to the source of your pain and neuropathy-related symptoms.

No surgery. No disc removal. No spinal fusion.
This is a targeted, minimally invasive procedure designed to reduce pain, improve function, and help you return to the activities you enjoy.

What Is Disc Biacuplasty?
Disc Biacuplasty is a minimally invasive procedure that treats pain originating from a damaged or irritated spinal disc. Many people live for years with disc-related pain caused by tiny tears, inflammation, and pain-sensitive nerve fibers within the outer wall of the disc — pain that doesn’t respond well to medication or physical therapy alone.
Using real-time C-arm fluoroscopic (X-ray) guidance, your physician precisely places specialized instruments into the affected disc. The COOLIEF® TransDiscal® system then uses cooled radiofrequency energy to gently treat the painful area, reducing pain signals from irritated nerves and easing inflammation — all without damaging surrounding healthy tissue.
Enhanced With Regenerative Therapy
What sets our approach apart is the addition of regenerative biologic therapies immediately following the Biacuplasty treatment. These therapies work with your body’s natural healing response to help reduce inflammation, promote tissue repair, and create a healthier environment within the treated disc.
Platelet-Rich Plasma (PRP)
concentrated growth factors from your own blood that signal and accelerate tissue repair.
Stem Cells
regenerative cells that support the body’s ability to repair and renew damaged tissue.
Exosomes
powerful cellular messengers that help coordinate healing and reduce inflammation at the source.
How the Procedure Works



Step 1
Imaging-guided precision: Real-time fluoroscopic guidance allows exact placement of instruments into the affected disc.
Step 2
Cooled radiofrequency treatment: When the disc is the source of pain or contributes to neuropathy-related symptoms, the COOLIEF® TransDiscal® system applies controlled heat within the disc to calm irritated nerve fibers and reduce disc-related pain signals.
Step 3
Regenerative biologics: PRP, stem cells, and exosomes are administered to support natural healing within the disc.
Step 4
Recovery & guidance: You’re given a structured recovery plan to guide your healing over the following weeks.
Enhanced With Regenerative Therapy
This procedure may be a good option for patients who:
-> Experience chronic low back pain or neuropathy-related symptoms originating from a damaged or degenerative disc
-> Have not found lasting relief from medication, physical therapy, or injections
-> Want a non-surgical alternative that avoids disc removal or spinal fusion
-> Are seeking a regenerative approach that supports the body’s natural healing
Explore our patient guide on Regenerative Disc Therapy
Is this right for you?
A consultation with our team is the best way to determine whether Disc Biacuplasty with regenerative therapy fits your specific condition and goals.