Ozone Therapy in Cabo San Lucas: A Patient's Guide to Regenerative Wellness
Welcome to your guide on ozone therapy, a sophisticated regenerative treatment drawing discerning individuals from the US and Canada to the restorative shores of Cabo San Lucas. At its core, this advanced medical therapy utilizes activated oxygen to stimulate your body’s innate healing mechanisms. It enhances cellular efficiency, improves oxygen utilization, and fortifies your system against the physiological stress of modern life.
A Premier Destination for Advanced Wellness
In recent years, Los Cabos has evolved beyond a premier vacation locale into a world-class destination for advanced wellness. It attracts individuals seeking the pinnacle of medical innovation within a tranquil, healing environment. Regenerative medicine is central to this transformation, offering scientifically grounded pathways to heal, recover, and proactively optimize long-term health.
This guide is designed to provide a clear, medically sound overview of ozone therapy and what a regenerative medicine journey in Mexico entails. We will explore the science, the process, and the clinical standards that define a truly premium patient experience, empowering you to make an informed decision about your health.
Why Cabo for Regenerative Therapies?
The appeal of Cabo for medical travel is rooted in its fusion of clinical excellence and a superior patient experience. The challenge for any prospective patient is identifying a clinic that not only meets their health objectives but also operates at the highest international standards of safety. Cabo has risen to meet that challenge, offering:
World-Class Facilities: Leading clinics are equipped with state-of-the-art technology and adhere to the rigorous clinical protocols expected of any top-tier medical institution.
Experienced Practitioners: The region has become a center for highly qualified physicians and medical teams specializing in regenerative and longevity medicine.
A Focus on the Patient Experience: Providers understand the needs of international patients, offering comprehensive support and concierge services to ensure a seamless and stress-free journey.
At Longevity Medical Institute, we provide a premium, physician-led experience for patients seeking to restore and optimize their vitality. Our entire approach is built on a foundation of rigorous science and compassionate, personalized care. We ensure every patient feels supported, from their initial consultation through their treatment, recovery, and beyond.
Our goal is to provide the detailed, practical information you need to confidently choose the right partner for your health journey. As you explore your options, you'll understand why our clinic is a leading choice for those seeking a regenerative medicine center in Cabo San Lucas that prioritizes patient well-being and clinical outcomes.
How Ozone Therapy Works at a Cellular Level
To understand ozone therapy, it is helpful to view the body as a high-performance biological system. Like any complex system, it functions best with optimal energy and efficiency. Ozone therapy acts as a biological enhancement, using a highly reactive form of oxygen—O₃ or activated oxygen—to optimize the function of your cellular powerhouses, the mitochondria.
This is not a simple process of increasing oxygen supply; it is a sophisticated biochemical intervention. A precisely controlled amount of medical-grade ozone is introduced to stimulate a powerful, systemic therapeutic response. This gentle, controlled oxidative challenge signals your cells to become more efficient and resilient, enhancing performance and promoting healing from within.
The objective is to modulate and optimize your body's innate functions, not override them.
Enhancing Oxygen Delivery and Cellular Energy
One of the primary benefits of ozone therapy is its profound effect on oxygen metabolism. When introduced into the bloodstream, ozone improves the ability of red blood cells to release oxygen into tissues, muscles, and organs.
This mechanism can be visualized as improving the efficiency of a delivery system. Ozone enhances both the capacity and the delivery speed of oxygen to its destination.
This enhanced oxygenation directly fuels your mitochondria. With more available oxygen, these cellular engines can produce more adenosine triphosphate (ATP), the body’s primary energy currency. The result is often a noticeable increase in energy, stamina, and mental clarity as the entire system begins to operate more efficiently.
The graphic below illustrates the core mechanisms through which ozone therapy supports the body.

As shown, activated oxygen improves the body's use of oxygen, helps modulate inflammatory responses, and strengthens its defenses against cellular stress.
Activating Natural Antioxidant Defenses
A key concept in longevity and wellness is oxidative stress, a form of cellular damage that occurs from metabolic processes, environmental exposures, and inflammation. While some oxidative stress is a normal part of physiology, chronic levels can accelerate aging and contribute to various health conditions.
Ozone therapy works by introducing a mild, controlled oxidative effect. This process, known as hormesis, is analogous to how exercise strengthens muscles by first inducing microscopic stress, which the body then adapts to and repairs, resulting in increased strength.
This controlled "stress" activates the body’s most powerful endogenous antioxidant and detoxification pathways, such as the Nrf2 pathway. By prompting your cells to produce their own protective enzymes, ozone therapy helps build long-term resilience against cellular damage, effectively training the body to better protect itself.
This mechanism is a primary reason ozone therapy is integrated into longevity and performance protocols. Instead of merely supplying external antioxidants, it fortifies the body's own defense systems. For patients interested in complementary treatments, hyperbaric oxygen therapy also supports cellular health through enhanced oxygenation.
This sophisticated, bio-regulatory approach is gaining significant attention from the medical community and patients alike. Ozone therapy is a frequently sought-after treatment for US and Canadian patients in Mexico, with some clinics in Los Cabos reporting over 1,100 procedures performed by specialists. Patients often report significant benefits, with satisfaction rates reaching 100% in verified reviews, noting up to 80% reductions in markers of chronic inflammation and pain.
For the 2.5 million US medical travelers visiting Mexico annually, ozone therapy has also been shown to enhance the efficacy of treatments like stem cell therapy by 40-50%.
Exploring Different Types of Ozone Therapy
Ozone therapy is not a monolithic treatment but a suite of administration methods, each designed to address specific clinical goals. At Longevity Medical Institute, our physicians select the most appropriate delivery route based on a patient's unique physiology and desired outcomes, ensuring a precise and effective therapeutic experience.
The choice of method depends on whether the goal is systemic, whole-body benefits—such as immune modulation and reduced inflammation—or targeted relief for a localized issue. Understanding these approaches is the first step toward a truly personalized treatment plan.
Each method is designed to safely introduce medical-grade ozone into the body to initiate the powerful healing responses discussed previously. Let’s explore the primary types of ozone therapy offered at our Cabo San Lucas clinic.
Major Autohemotherapy for Systemic Wellness
Major Autohemotherapy (MAH) is the most common and widely studied method of systemic ozone therapy. It is a closed-loop, sterile procedure that delivers potent, body-wide benefits. The process is straightforward and comfortable, comparable to a standard IV infusion.
During an MAH session, a small volume of your blood is drawn into a sterile IV bag. This blood is then carefully mixed with a precise concentration of medical-grade ozone gas. Once enriched, the ozonated blood is reinfused back into your body, where it circulates and exerts its therapeutic effects.
This method is highly effective for addressing systemic inflammation, supporting immune modulation, and improving overall cellular energy. By treating the blood directly, MAH ensures the benefits of activated oxygen are distributed throughout the entire system, making it an excellent choice for chronic conditions and proactive wellness.
For patients requiring a more intensive protocol, we also offer the advanced 10 Pass method. This technique repeats the MAH process up to ten times in a single session, delivering a significantly higher dose of ozone for a more profound therapeutic effect.
Rectal Insufflation: A Powerful Alternative
While MAH is highly effective, Rectal Insufflation (RI) offers an excellent alternative for achieving systemic results. This method is minimally invasive, highly efficient, and is often utilized for patients who may have difficult IV access or prefer a non-intravenous option.
The procedure involves the gentle introduction of an ozone-oxygen gas mixture into the colon. The colonic mucosa is highly permeable and has a rich vascular supply, which allows the ozone to be absorbed rapidly into the circulatory system.
High Absorption Rate: The colon's extensive network of blood vessels ensures ozone is quickly absorbed and distributed systemically, with effects comparable to intravenous methods.
Gut Health Support: This method can also provide localized benefits to the gastrointestinal tract, helping to support a healthy gut microbiome and reduce local inflammation.
Comfort and Convenience: The procedure is quick, typically taking only a few minutes, and is generally very well tolerated.
Rectal insufflation is a safe, established method for delivering ozone systemically, making it a versatile tool in our regenerative protocols.
Topical Ozone for Localized Conditions
Not all health concerns are systemic. For targeted skin conditions, non-healing wounds, or localized infections, Topical Ozone Therapy provides a direct and effective solution. This method involves applying ozonated oils or enclosing a specific body part in an ozone-filled bag to deliver ozone directly to the affected tissue.
Ozonated oils are produced by bubbling ozone gas through high-quality olive or sunflower oil for an extended period. This process traps ozone within the oil, creating a powerful salve with antimicrobial and tissue-regenerating properties. Applying these oils can help accelerate wound healing, address skin infections, and reduce localized inflammation. For a deeper understanding of our advanced protocols, you can explore our overview of TriFusion Ozone Therapy.
To help visualize how these common methods compare, we have prepared a table outlining their key differences.
Comparing Ozone Therapy Administration Methods
This table provides a clear comparison of the most common ozone therapy methods, helping patients understand the application, primary use, and what to expect from each.
Each of these methods offers a unique way to harness the therapeutic power of ozone. The optimal approach is always determined during a physician consultation and is precisely aligned with your specific health objectives.
Your Patient Journey: From Consultation to Recovery
Embarking on a regenerative therapy journey should be an empowering and clear process. We have designed every step of your ozone therapy Cabo San Lucas experience at Longevity Medical Institute to be transparent, comfortable, and centered on your personal health goals.
Our process is a structured roadmap, guiding you from your initial conversation with our team through your personalized treatment and recovery, ensuring you feel confident and cared for at every stage.
Step 1: The In-Depth Physician Consultation
Your journey begins with a comprehensive consultation with one of our licensed physicians. This is a deep exploration of your health history, current wellness status, and specific objectives. We listen carefully, whether your goal is to address chronic symptoms, accelerate athletic recovery, or proactively enhance your vitality.
This initial consultation is critical. It is where we determine if ozone therapy is the appropriate intervention for you and which administration method will be most effective. Based on this thorough evaluation, our medical team designs a personalized treatment protocol tailored to your unique biology.
A successful outcome always begins with a precise diagnosis and a clear, physician-guided plan. Your physician will explain the recommended approach, answer all of your questions, and ensure you have a complete understanding of the process before moving forward.
This collaborative approach ensures your treatment plan is not only scientifically sound but also perfectly aligned with your personal health aspirations.
Step 2: Your Treatment Day Experience
On the day of your appointment, you will be welcomed into our calm, professional clinic—a serene environment designed for healing and relaxation. Our expert medical team is dedicated to your comfort and safety, guiding you through every moment of the procedure.
Your treatment will be administered in a private, sterile suite by a qualified medical professional under direct physician supervision. We use only medical-grade ozone generators and single-use, sterile equipment to meet the highest standards of safety.
Patient Comfort: Whether you are receiving Major Autohemotherapy or another form of ozone therapy, our team will ensure you are comfortable and relaxed throughout the session, which typically lasts between 30 and 60 minutes.
Clinical Monitoring: Your well-being is our top priority. Our clinical staff remains with you during the treatment to monitor your experience and provide immediate support.
Post-Treatment Guidance: Before you leave, we will provide clear aftercare instructions to help maximize the benefits of your therapy and support your body’s regenerative response. You can also track your progress and communicate with our team through our proprietary Longevity Patient App.
Step 3: Post-Treatment Care and Follow-Up
The therapeutic benefits of ozone therapy often continue to unfold in the hours and days following your session. Many patients report an increase in energy, mental clarity, and an overall sense of well-being.
It is also possible to experience mild detoxification symptoms, such as transient fatigue, as your body clears cellular waste. We encourage you to stay well-hydrated and rest as needed to support this natural process.
Our medical team is always available to answer any questions that may arise during your recovery. We are committed to your long-term success and will schedule follow-up communications to monitor your progress and make any necessary adjustments to your care plan. Your journey with us is a partnership dedicated to achieving lasting health.
Upholding the Highest Standards of Safety and Quality
When traveling for medical care, trust is paramount. At Longevity Medical Institute, our clinical philosophy is built on an unwavering commitment to patient safety and excellence. We understand that discerning patients from the US and Canada expect a standard of care that meets or exceeds what they find at home, and our entire infrastructure is designed to deliver on that expectation.
Every aspect of our clinical operation is structured to provide complete peace of mind. We adhere to rigorous international standards, ensuring that your ozone therapy in Cabo San Lucas is managed with the utmost precision from start to finish.
COFEPRIS and ISO Certified Excellence
A cornerstone of our commitment is our official licensing and certification. Our clinic operates under the strict oversight of COFEPRIS, Mexico's federal agency for regulating medical facilities and biologics, which is the direct equivalent of the FDA in the United States. This license is your guarantee that our facility, equipment, and protocols meet demanding national safety standards.
Furthermore, our on-site biotechnology laboratory is ISO-certified, holding us to globally recognized benchmarks for quality management and sterile processing. This dual accreditation provides a powerful, multi-layered assurance of quality and safety.
When you receive ozone therapy at our institute, you can be confident that the medical-grade ozone is generated by state-of-the-art equipment and administered with sterile, single-use materials under the direct supervision of our licensed medical team.
The Critical Role of Physician-Led Care
While ozone therapy has a strong safety profile when administered correctly, it is a medical procedure that requires expert oversight. Certain underlying conditions can pose contraindications, making a thorough medical evaluation essential before beginning treatment.
That is why every ozone therapy protocol at our institute begins with a comprehensive physician consultation. Our medical director personally oversees all treatment plans, ensuring the therapy is not only safe but also appropriate for your specific health needs and goals.
Common Contraindications We Screen For:
G6PD Deficiency: A genetic disorder that can affect red blood cell stability.
Active Bleeding or Hemorrhagic Conditions: As ozone can influence blood coagulation.
Uncontrolled Hyperthyroidism: Due to ozone's potential to influence metabolic rates.
Pregnancy: As a precautionary measure, ozone therapy is not recommended during pregnancy.
This rigorous, physician-led approach is non-negotiable for both safety and efficacy. By carefully screening each patient and tailoring the treatment to their unique physiology, we ensure optimal outcomes while minimizing potential risks. Our dedication to safety is a primary reason patients entrust us with their care. You can learn more about our commitment to trust, safety, and transparency in our comprehensive guide.
By integrating advanced facilities, uncompromising sterile techniques, and the direct oversight of our medical director, we have created a trustworthy environment for patients seeking safe, effective regenerative care in Mexico.
Why Patients Choose Our Cabo San Lucas Clinic
Choosing a clinic for regenerative medicine is about more than a single treatment—it is about finding a partner you can trust with your long-term health. Patients seeking ozone therapy in Cabo San Lucas consistently choose Longevity Medical Institute because our philosophy is built on a foundation of integrated, physician-led care.
We don’t just administer therapies; we create comprehensive programs that integrate advanced treatments for synergistic results.
Our approach is grounded in precision and personalization. We view ozone therapy not as a standalone solution, but as a powerful foundational tool. It prepares the body for deeper healing by enhancing circulation, modulating inflammation, and optimizing cellular function. This creates the ideal biological environment for other advanced treatments to work more effectively.
An Integrated Approach to Healing
At our clinic, ozone therapy is thoughtfully combined with other cutting-edge regenerative protocols. This multi-modal strategy is designed to amplify the body's natural healing capabilities, delivering results that are often greater than the sum of their individual parts.
For example, we frequently pair ozone therapy with:
Stem Cell and Exosome Therapies: By improving the cellular microenvironment, ozone helps create a more receptive foundation for these powerful regenerative biologics to thrive and perform their reparative functions.
Advanced IV Infusions: Custom nutrient and peptide infusions can be administered alongside ozone to provide specific building blocks the body needs for recovery and optimization.
Hyperbaric Oxygen Therapy (HBOT): Combining these two oxygen-based therapies can produce a powerful synergistic effect against inflammation and cellular stress.
This integrative model ensures every aspect of your health is supported, moving you closer to your wellness goals with a scientifically grounded and cohesive plan.
The Longevity Medical Institute Difference
What truly sets us apart is the seamless fusion of clinical excellence with a patient-first philosophy. Your entire experience is managed by our in-house team of physicians in a serene, professional environment designed for your comfort and confidence.
Your journey with us is defined by clarity and unwavering support. From your initial in-depth consultation and advanced in-house diagnostics to our dedicated concierge services, every detail is managed to ensure a stress-free experience.
We handle all logistics so you can focus on what matters most—your health. Receiving world-class medical care in the beautiful, restorative setting of San José del Cabo allows you to heal on every level. Our commitment is to help you achieve your health goals with the highest standards of safety, expertise, and personalized care.
Your Questions About Ozone Therapy Answered
Exploring a new medical therapy is a significant step, and it is natural to have questions. We believe that clarity is essential for making confident health decisions. This section provides straightforward answers to the most common questions we receive about ozone therapy in Cabo San Lucas.
Our goal is to provide the information you need to move forward feeling informed and empowered.
Is Ozone Therapy Safe When Administered By a Professional?
Yes. When administered by a qualified medical team following established clinical protocols, ozone therapy has an excellent safety record. At Longevity Medical Institute, every treatment is physician-supervised and conducted within a licensed medical facility, ensuring the highest standards of care.
We use only medical-grade ozone generators and sterile, single-use equipment. Crucially, no treatment begins without a comprehensive medical evaluation. This allows our physicians to confirm that the therapy is appropriate for your specific health needs and to rule out any contraindications, making your safety our top priority.
How Many Ozone Therapy Sessions Will I Need?
The number of sessions required is entirely dependent on your personal health goals and the condition being addressed. A successful protocol is always a personalized one.
For a patient working to resolve a chronic health issue or as part of a comprehensive regenerative plan, a series of 5 to 10 sessions may be recommended to achieve a cumulative therapeutic benefit. Conversely, for general wellness, athletic recovery, or performance optimization, fewer sessions may be sufficient. Your physician will outline a tailored plan during your initial consultation, clearly defining the number and frequency of sessions needed to achieve your desired results.
Can Ozone Therapy Be Combined With Stem Cell Therapy?
Yes, and this combination is often recommended. Ozone therapy is an excellent complementary treatment that works synergistically with other regenerative therapies. Its ability to enhance circulation, modulate systemic inflammation, and improve oxygen delivery creates the ideal biological environment for treatments like stem cell and exosome therapy to perform optimally.
Think of it as preparing fertile soil before planting a seed. By optimizing the cellular landscape first, ozone therapy gives powerful regenerative biologics the best possible chance to engraft, differentiate, and carry out their reparative functions.
We specialize in designing these integrated protocols. Leveraging the combined power of multiple therapies is a cornerstone of our approach, helping us maximize patient outcomes and support a deeper, more lasting level of healing.
What Does an Ozone Therapy Session Feel Like?
Most of our patients describe the experience as comfortable and relaxing. For systemic treatments like Major Autohemotherapy (MAH), our most common method, the procedure feels nearly identical to receiving a standard IV infusion.
The session itself typically lasts between 30 to 60 minutes, during which you will be resting comfortably in a private treatment suite. The only sensation is usually a small pinch from the initial needle insertion. Many patients report a subtle increase in energy or a sense of calm during or immediately after the session, with no significant discomfort involved. Our clinical team remains with you throughout the entire process to ensure you feel safe and supported.
Considering Stem Cell Therapy in Cabo San Lucas, Mexico?
Cabo San Lucas, Mexico is part of the greater Los Cabos medical corridor and serves patients traveling to the region for regenerative and longevity-focused care.
Longevity Medical Institute coordinates physician-supervised regenerative services for patients in Cabo San Lucas, Mexico, emphasizing appropriate candidacy, clinical oversight, and informed decision-making. This approach allows patients to explore regenerative therapies within a regulated medical setting.
Longevity Medical Institute is the only COFEPRIS federally licensed medical clinic and biotechnology laboratory in Cabo San Lucas, Mexico, delivering regulated, science-backed regenerative and longevity care under Mexico’s highest clinical standards.
Learn more about regenerative medicine options near Cabo San Lucas.
Author
Dr. Kirk Sanford, DC — Founder & CEO, Longevity Medical Institute. Dr. Sanford focuses on patient education in regenerative and longevity medicine, translating complex therapies into clear, practical guidance for patients.
Medical Review
Dr. Félix Porras, MD — Medical Director, Longevity Medical Institute. Dr. Porras provides clinical oversight and medical review to help ensure accuracy, safety context, and alignment with current standards of care.
Last Reviewed: June 10, 2025
Short Disclaimer
This information is for educational purposes only and is not medical advice. It does not replace an evaluation by a qualified healthcare professional. For personalized guidance, please schedule a consultation.