Regenerative Neurological Therapy
Why Ordinary Nasal Sprays Fall Short
Most sprays deposit medication in the lower nasal passages, where it’s absorbed into the bloodstream or simply swallowed. Very little reaches the olfactory region at the top of the nasal cavity, the small area with a direct anatomical connection to the brain. In fact, with a standard spray pump, less than 3% of the dose reaches that region. This platform was engineered specifically to solve this.
How It Works
Rather than a quick burst, the system uses an electronically controlled nebulizer to create a gentle vortex of microscopic droplets, delivered as a slow, controlled aerosol over several minutes. This is designed to target the olfactory region, increase contact time with the nasal lining, reduce loss into the throat, and improve the consistency of delivery, all of which support the potential for nose-to-brain transport.
Why It Matters
Intranasal delivery has become one of the fastest-growing areas of neurological research because it offers a way to reach the central nervous system without surgery or spinal injections. The ability of specialized devices like the one we use to deposit compounds in the olfactory region and reach the brain is well documented: studies using this route have shown measurable delivery to the brain within minutes, and the device has been used in numerous registered clinical trials for conditions including post-stroke recovery, multiple sclerosis–related cognitive impairment, and other neurological disorders.
Our Regenerative Approach
At Longevity Medical Institute, we use this platform exclusively for delivering regenerative therapies: stem cells (MSCs), exosomes, and selected peptides. Our physicians determine whether intranasal delivery, intravenous therapy, intrathecal administration, or a combination is most appropriate for your diagnosis and goals.
Choosing the Right Delivery Route
We offer both intranasal and intrathecal delivery, and our physicians recommend whichever fits your diagnosis, goals, and condition.
Intranasal delivery is non-invasive, requires no spinal needle, and is performed as a clinic-based procedure. It’s well suited to patients seeking a less invasive approach, or who are not candidates for, or prefer to avoid, a spinal procedure.
Intrathecal injection delivers therapy directly into the cerebrospinal fluid through a lumbar puncture. It provides the most direct route to the central nervous system, and we perform it in our fully licensed operating room when a patient’s condition calls for direct cerebrospinal fluid delivery.